ADVANCED BIOPOLYMERS AS
Advanced Biopolymers AS is a Norwegian high tech company
specialising in the production of high quality chitosan
with a very
broad range of degrees of acetylation (DA), with focus
with DA between 0.25 and 0.60. We use our simple,
and patented technology to produce these chitosans,
in one step
and with unsurpassed reproducibility.
Chitosan with DA between 0.25 and
0.60 have an increased solubility in water at higher
pH-values. Generally, the water solubility of chitosans
are determined by pH (protonisation of the amino group),
the ionic strength of the solvent and the ions interacting
with the chitosan. Traditional commercial chitosans
precipitate between pH 6 and 6.5, and are insoluble
at physiological pH-values (7.2-7.4). However, our
chitosans, characterised by higher DA values are soluble
also at physiological pH, (Ref.: Carbohydr. Polym.
(1994) 25, 65-70).